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When You Need it MostImmunoREV supershot is a convenient, on the spot way to boost your immune system when you need it most. Results are fast acting and safe.*
IngredientsAndrographis (Andrographis paniculata) (stem), N-Acetyl L-Cysteine (NAC), Beta Glucan (Avena sativa) (seed bran), Elderberry (Sambucus nigra) (fruit), Astragalus (Astragalus membranaceus) (root), Olive Leaf Extract (Olea europaea) (leaves), Oregano Oil (Origanum vulgare) (leaf), Garlic Clove (bulbs) (Allium sativum), Maitake Mushroom (Grifola frondosa), Shiitake Mushroom (Lentinula edodes) with natural flavors Mint & Xylitol.
Other Ingredients: Ultra-Pure Deionized Water
* % Daily value not established
All products are:
Seasonal & Ongoing Immune SupportRegular use of ImmunoREV supershot is the key to seasonal and continual immune support promoting optimal health for today and tomorrow.*
Andrographis paniculata (family Acanthaceae) is a popular medicinal plant whose constituents have been used traditionally for an array of upper respiratory conditions. Phytochemical constituents have been shown to be effective at reducing the incidence and intensity of seasonal respiratory symptoms.1,2
N-acetyl-L-cysteine (NAC) has been shown to possess powerful antioxidant activity and decrease viral load and replication. NAC also diminished the release of inflammatory cytokines and apoptotic mediators.3,4
Beta 1,3 Glucan:
Glucans are a group of linked glucose carbohydrates that are also known to be biologically active immunomodulators or biological response modifiers. The strong immunostimulating potential of β-glucans has been well established. Glucan feeding has been shown to improve phagocytosis and NK cell activity, improve inflammatory cytokine profiles and significantly lessen symptoms of seasonal respiratory issues, illustrating beta-glucan’s ability to defend against invading pathogens.5,6
Sambucus nigra (Elderberry):
Research in an animal models has shown Sambucus nigra L. extract (elderberry juice) suppresses viral replication, modulate serum antibody levels to combat pathogens, and raises secretory IgA levels, demonstrating an immune-stimulating response. Elderberry has been shown to lessen the incidence and duration of seasonal respiratory disorders.7,8
Preclinical research has demonstrated Astragalus polysaccharides possess inhibitory activity against certain respiratory pathogens. Astragalus has also been shown to modulate antibody titers to combat pathogens, improve proinflammatory cytokine profiles and enhance early humoral immune responses.9,10
Olea europaea (Olive Leaf Extract):
Olive leaf extracts have been shown in vitro to increase absolute numbers of CD8+ cells and natural killer (NK) cells, production of interferon-gamma as an expression of T helper 1 activation, and elevate nitric oxide production, suggesting it enhances a healthy immune response. Oleuropein, a powerful constituent of Olea europaea, also appears to inhibit some upper respiratory pathogens.11,12
Origanum vulgare (Oregano Oil):
Oreganum vulgare (oregano) extract contains a number of important constituents possessing antioxidant, cytotoxic, and pathogen-modulating activities. These important properties are primarily attributed to oregano’s carvacrol and thymol constituents. Carvacrol has been shown to reduce structural integrity and promote inactivation of some respiratory pathogens.13,14
Allium sativum (Garlic Clove):
Allium sativum (garlic clove) has significant research to support its many beneficial effects, which are attributed, at least in part, to its allicin constituent. The use of allicin-containing garlic supplements may modulate the incidence and duration of common seasonal respiratory illnesses. Recently Allium sativum research has demonstrated that it modulates cytokine secretion, possibly providing a mechanism of action for its many therapeutic effects related to immune function.15,16
Grifolia frondosa (Maitake Mushroom):
Maitake mushrooms (Grifola frondosa) are popular in Asia for immune-stimulating properties and research supports these benefits. Clinical research indicates Maitake mushroom consumption may modulate antibody titers in response to vaccination and is also effective in improving symptoms during seasonal respiratory illness.17
Lentinula edodes (Shiitake Mushroom):
Clinical research has demonstrated that consuming Shiitake (Lentinula edodes) mushrooms daily improved cell effector function and increases secretory IgA, suggesting improved gut immunity. Shiitake mushroom consumption also improved C-Reactive Protein levels and cytokine profiles, suggesting a decrease in inflammation and an overall enhanced immune response.18 A combination of natural immunomodulating glucans from Maitake and Shiitake mushrooms given over a two-week period strongly stimulated both cellular and humoral immune response at a significantly higher level than either mushroom alone, or that of active hexose correlated compound.19
1. Cáceres DD, Hancke JL, Burgos RA, et al. Phytomedicine 1999;6:217-223.2. Melchior J, Palm S, Wikman G. Phytomedicine 1997;3:315-318.
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